DeSmuME Wii is a port of the Nintendo DS emulator DeSmuME to Wii homebrew.
At this point, 95% of DS games should be able to be booted and about 30% of those should be fully playable.
News source: http://wiibrew.org/wiki/DeSmuME_Wii
http://arikadosblog.blogspot.com/2010/04/desmume-wii-r154-released.html
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