Remote Touch DS gives you the opportunity to remote-control your computers mouse, keyboard and other things from your Nintendo DS hand-held console. This solution is not like remote desktop, but more like an advanced remote control.

The solution is client-server based, obviously, and requires you to have a server running.

Release notes:

0.6 (major)
* Up on D-pad in “cursor”-mode for middle mouse click.
* Complete revamped server-backend rewritten in Java with full GUI (will work cross-platform; Windows and OS X/*unix etc.).
* Add support for custom key-mapping (gamepad-like feature) – configure this with the new server-backend GUI.
* Custom adjustment of mouse acceleration.

http://forum.gbadev.org/viewtopic.php?t=16687