UAE Wii is a port of the famous Amiga emulator UAE and is based on the source code of E-UAE. The port uses SDL Wii.
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Epic Realtime released by Genesis Project at tUM 2012.
ZXDS is an emulator of Sinclair ZX Spectrum for Nintendo DS, written by Patrik Rak. It is steadily reaching a mature stage of development, and it already has some noteworthy features, like accurate emulation of Spectrum 48k, 128k and Pentagon models (including sound), or support for TAP/TZX/PZX tape files, TRD/SCL disk files and RZX playback files.
GemRB (Game engine made with pre-Rendered Background) is a portable open-source implementation of Bioware's Infinity Engine.
Kobo Deluxe by David Olofson is an enhanced version of Akira Higuchi's game XKobo for Un*x systems with X11. Kobo Deluxe adds sound, smoother animation, high resolution support, OpenGL acceleration (optional), an intuitive menu driven user interface, joystick support and other features. Recent versions also add a number of alternative skill levels with slightly modernized gameplay. Kobo Deluxe uses SDL for graphics, sound and input, which makes it possible to build and run the game on pretty much anything.
Rockbox is an open source firmware for mp3 players, written from scratch. It runs on a wide range of players.
Locomalito's game L'Abbaye des Morts ported to Pandora! The gameplay is directly inspired by Manic Miner and Jet Set Willy.
Stiled by Missing Dragonfly Studio is a puzzle game where the player has to complete puzzles based on tiles! While also being accompanied by synchronized music and player generated beats, the player can advance from casual to hardcore levels, in two different and fun game modes.
WiiEarth by Paul Wagener allows you to use your Wiimote to navigate (and zoom-in on) the Earth, using Google Maps and similar services. You can switch between viewing with OpenStreetMap, Live (Maps, Satellite) and Google (Maps, Satellite, Terrain).
Family Picross by freem is a Picross game for NES/Famicom. The game is playable but still considered a demo. Improvements should be seen the next couple of weeks.